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Common question: Do we vaccinate patients with immune impairment? This group, which includes patients on chemo, transplant recipients, HIV, etc. are at high risk, but there's little data on vaccine performance in these groups.
How much can we extrapolate from healthy volunteers?
How much can we extrapolate from healthy volunteers?
This becomes an issue when we try to anticipate how #COVID19 vaccines will perform in nursing home residents. Very few (if any?) were included in the tens of thousands who volunteered for studies. Does that matter?
The ACIP vote on vaccine priority was not unanimous because...
The ACIP vote on vaccine priority was not unanimous because...
...one expert was concerned about the potential effects of COVID vaccine on residents of long-term care facilities. The elderly typically have weaker immune responses to vaccines and there needs to be a robust safety surveillance system for these patients. https://www.sciencemag.org/news/2020/12/cdc-advisory-panel-takes-first-shot-prioritizing-who-gets-first-shots-covid-19-vaccines
The issue of extrapolation will impact a very large swath of the population, including patients who have medical conditions that cause mild immune impairment or take medications that subtly alter the immune system.
Physicians are already asking me if dosage adjustments are warranted. There's no easy answer to that question.
It is difficult to ask for more time and more data when so many are dying every day, but truth be told, that's what many doctors want.
It is difficult to ask for more time and more data when so many are dying every day, but truth be told, that's what many doctors want.
