I& #39;m working on a #DataScience project that leverages data from @CancerDepMap.

The goal is to:
- discover new functions for known genes
- find functions for unknown genes
- identify new therapeutic targets

Ready, go. https://twitter.com/JamesClear/status/1263511239793217536">https://twitter.com/JamesClea...

If you didn& #39;t know anything about MTOR, you& #39;d basically map the entire pathway that @DMSabatini and co. worked out

Same for TSC1/TSC2 that @Manning_BD and co are drilling down on

*Notice the inverse pattern between these two

(cc @tsalliance)

Another & #39;master& #39; regulatory LKB1 shows several known relationships, including @LabReuben& #39;s recent SIK targets

And what & #39;hairball& #39; would be complete without P53?

(see pinned tweet https://abs.twimg.com/emoji/v2/... draggable="false" alt="😂" title="Face with tears of joy" aria-label="Emoji: Face with tears of joy">)